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A research team has discovered a pair of tissue biomarkers that directly contribute to the harmful joint degeneration associated with spine osteoarthritis.

Researchers at Iowa State University have discovered what could lead to a new treatment for spinal muscular atrophy, a potentially fatal genetic disorder in young children.

Physicians at Rush University Medical Center became the first in Illinois to inject AST-OPC1 (oligodendrocyte progenitor cells), an experimental treatment, into the damaged cervical spine of a recently paralyzed man as part of a multicenter clinical trial.

For the first time, scientists found that in spinal muscular atrophy (SMA), the affected nerve cells that control muscle movement, or motor neurons, have defects in their mitochondria, which generate energy used by the cell. Impaired mitochondrial function and structure in motor neurons were discove...

Patients who underwent primary hip arthroscopy experienced greater improvement in patient-reported outcome scores at 2-year follow-up compared with patients who underwent revision arthroscopy, according to recently presented data.

Morbidly obese patients who underwent aseptic revision total hip arthroplasty experienced similar complications, failures and clinical outcomes compared with nonobese patients, according to study results.

Carlen Reyes, M.D., Ph.D., from Universitat Autònoma de Barcelona in Spain, and colleagues conducted a population-based cohort study using primary car...

Hip ROM does not change to a clinically significant extent with induction of general anesthesia. Small increases in external rotation in patients with FAI or acetabular dysplasia are within the standard error for ROM measurements.

Achilles tendinopathy is a common lower extremity injury in athletes as well as nonathletes. The Achilles tendon is often a site of injury in runners and is the second-most common running-related musculo­skeletal injury, after medial tibial stress syndrome, with an incidence of 9.1% to 10.9%.1 The...

Researchers are investigating how changes during pregnancy may affect the lower extremities in the long term, as well as ways to treat and prevent these issues.